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Our laboratory aims at investigating the effects of increased (hyperoxia) or decreased (hypoxia) oxygen concentrations through a various panel of markers involving iron. One is dependent on a higher percentage of nitrogen in the inhaled mixture at atmospheric pressure. To reach hypoxic oxygen levels, two different modalities are possible

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One is dependent on a higher percentage of nitrogen in the inhaled mixture at atmospheric pressure (normobaric. The sensing of decreased oxygen levels (hypoxia) or increased oxygen levels (hyperoxia), occurs through specialized chemoreceptor cells and metabolic changes at the. Hyperoxia is the opposite of hypoxia

Hyperoxia refers to a state in which oxygen supply to the tissues is excessive, while hypoxia refers to a state in which oxygen supply is insufficient.

The study organized patients into three oxygen exposure groups based on pao2 values obtained in the ed after intubation Here, we review the existing literature regarding the ability of brain to adapt to chronic hypoxia and chronic hyperoxia with analysis of the metabolic and molecular changes.