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Androgen deprivation therapy (adt) alone was for decades the standard of care for treating mhspc There are many ways to control advanced prostate cancer. This changed when studies showed.

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Treatment of metastatic prostate cancer is generally based on whether its growth can be slowed or stopped with hormone therapy When prostate cancer spreads beyond the prostate or returns after treatment, it is often called advanced prostate cancer Recall that testosterone (an androgen hormone) is the “fuel” that makes prostate cancer cells grow

Both disease phases hold similar challenges and questions

Is there an optimal therapy sequence to maximize disease control and balance treatment burden Introduction the last decade has seen a seismic shift in the treatment landscape of metastatic hormone sensitive prostate cancer (mhspc) This includes several guideline and fda approved doublet therapy options, triplet therapy options, and treatment with radiotherapy to the primary tumor The selection of suitable patients for each therapeutic approach has become a determining factor to ensure efficacy and.

1 despite major improvements in the systemic treatment of advanced prostate cancer, metastatic prostate cancer remains an incurable disease with an overall survival (os) of only 30% at 5. There is a wide selection of therapies available for advanced prostate cancer treatment, but the optimal strategy for them is still pending.

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