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Growth differentiation factor 15 (gdf15) is a novel biomarker in the setting of pancreatic adenocarcinoma (pdac) Background cancer cachexia is a metabolic disease characterized by unintentional weight loss, anorexia, muscle and fat wasting, fatigue and muscle weakness, chronic inflammation, all of. Preliminary studies have found that downstream effects.

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Its levels have been shown to be upregulated in patients with cc, as well. Almost eighty percent of advanced cancer patients are affected by. Growth differentiation factor 15 (gdf15) has emerged as a key biomarker and therapeutic target in oncology, with roles extending beyond cancer cachexia.